Can leaky gut lead to autoimmune diseases?

Here at Healthpath, we’re proud to offer evidence-based advice. However, we’re aware that science can seem a bit impenetrable and dry. Boring, even.

We also believe that education is the first step to regain control. We read a lot of scientific papers, so we thought it would be a good idea to create a digest (no pun intended) of some of the key research.

We hope these plain-English versions bring the science to life and—even more importantly—help you address your symptoms for good.

 

“Leaky Gut As a Danger Signal for Autoimmune Diseases”

 

What’s the title in plain English?

Leaky gut may be a sign of autoimmune disease

 

What did they do?

In this 2017 literature review, the authors discuss the evidence in support of intestinal permeability—otherwise known as leaky gut—in the development of autoimmune disease.

 

What are the take-home points from the study?

1. In healthy people, the digestive tract and gut wall is a physical barrier held together by our gut bacteria, immune cells and mucous. If the gut lining becomes weak, toxins, antigens, and bacteria can ‘leak’ through this barrier into the bloodstream. This triggers an immune response.

2. The authors suggest that infection, alcohol consumption, a poor diet and stress are potential triggers that disrupt the gut barrier. These can lead to leaky gut and immune dysfunction.

3. Type-1 diabetes and systemic lupus erythematosus are two conditions that are discussed in detail. The authors speculate that leaky gut may contribute to the development of these autoimmune conditions, as well as others. The authors then suggest that prebiotics and probiotics could be a good choice for those with leaky gut.

The Healthpath view

Genetic and environmental factors can play a significant role in changes within the gut microbiome. Addressing gut health could be especially valuable for those with leaky gut and/or those at risk of autoimmune conditions.

 

Read the full published study here.

Ref: Mu, Q., Kirby, J., Reilly, C.M., Luo, X.M. and Rizzetto, L., 2017. Leaky Gut As a Danger Signal for Autoimmune Diseases. 8(May), pp.1–10.

Other articles you might like

Splitit

Interest free monthly payments

The benefits of choosing Splitit

  • No credit check
  • 0% interest
  • Never any late fees
  • No application or registration
  • Instant approval
  • Works with your existing credit

How Splitit works

Splitit Choose splitit at Checkout
Splitit Select number of payments
Splitit Order Complete

Example

At the time of purchase, you will only be charged for the first payment. On the same day of the following month your card will be charged the second payment and so on for each remaining month of the purchase plan.

To be eligible, you must own a Visa or Mastercard credit or debit card and have the entire amount of your purchase available on your card at the time of authorisation.

Debit cards have a maximum transaction value of £400 per transaction. If you require to spend over this amount, you may carry out two transactions. Credit cards have no maximum.

Splitit works by pre-authorising you payment card and then splitting the payment down into monthly charges. There is no extra charge for this service.

OK

We understand what you are going through.

Request callback

Talk to us about the best path forward.

Healthpath was born from personal experience. Our practitioners struggled with various symptoms before finding their resolutions—so they understand how frustrating it can be. But with our first-hand experience and our clinical expertise, we know gut health inside-out. Talk to us to see how we can help.


Alternatively, call us on +44 (0)207 193 1693 or email hello@healthpath.com